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The Rise And Fall Of Blood Glucose - learn with Fun

The Rise And Fall Of Blood Glucose - learn with Fun

Actors :
  • Pancreas
  • Muscles
  • Liver
  • Adipose tissue (fat)
  • Small intestine
  • 9 Glucose/Glycogen molecules
  • Insulin Blue Wizard (Glucose converter)
  • Glucagon Red Wizard (Glycogen breakdown)

Act I

Pancreas : I am the pancreas, and I secrete some very important hormones to help keep your body in perfect balance. One of these hormones you may have heard of before; it’s called insulin. When glucose, which is a sugar, is high in the blood, I release insulin to help bring the glucose level back to normal by helping glucose (sugar) from the food you eat to become stored in the body until you need it. Stored sugar is called glycogen. Let me show you how this works. Let’s say you just ate lunch.

Glucose Molecules : Four Glucose Molecules are moving around in the bloodstream (Five glucose molecules move out from behind the small intestine. Wow! Are we glad to get out of the digestive system! (Glucose Molecules move around the middle of the room) Where are we? Where is our home?

Pancreas : (To the audience) Notice that they’re too many Glucose Molecules in this blood right now. So, I will release some insulin to bring the blood glucose level back down. (Pancreas releases Insulin Blue Wizard).

Insulin Blue Wizard : Hey, let me show you your new home. Five Glucose molecules follow Insulin Blue Wizard to the liver, muscles, or adipose (fat) tissue. The Blue Wizard lightly taps each of the five Glucose Molecules on the shoulder with a wand and says, “Transform!” (Switch labels). This changes each Glucose Molecule into a Glycogen Molecule.

Pancreas, Glucose Molecules, and Insulin Blue Wizard perform the Insulin Rap

Insulin Insulin!
Storing sugar is so much fun
Muscles, liver, fat that's right
Get sugar each time you take a bite


Act II

Pancreas : But having only one job is boring and I am a born multitasker, so I also secrete a different hormone you may not have heard of before; it’s called glucagon. Glucagon is a hormone that breaks down the glycogen I help store in the liver, muscles, or adipose tissue, so your cells can keep on eating even when you’re not or when you are sleeping. Let me show you how this works. Let’s say lunch is over now and it’s time to catch a few Z’s.

Glucose Molecules : Only two Glucose Molecules are moving around in the bloodstream.

Pancreas : What’s Up? The blood glucose level is too low! We need more Glucose Molecules in the blood (releases two Glucagon Red Wizards into the blood).

Glucagon Red Wizard : The Glucagon Red Wizard goes over to the muscles and lightly taps glycogen on the shoulder with a wand and says, “Transform!” (Switch labels). This changes glycogen back to glucose.

Glucose : The two Glucose molecules move out of the muscles and back into the blood. Since there are four glucose molecules in the blood now, everything is in balance again.

Pancreas, Glucose, and Glucagon Red Wizard perform the Glucagon Rap.
Glucagon, glucagon
For in between meals and until dawn


Formative assessment :
Assume the blood glucose level is high. Place the cards in order to show the sequence of events. Begin with the pancreas.

Pancreas secretes insulin.   Glucose is converted to glycogen. Glucose is also transported to cells.   Blood glucose level drops, which inhibits insulin secretion.  
 
  Blood glucose level rises inhibiting glucagons secretion.   Breakdown glycogen to glucose; glucose released from cells.   Pancreas secretes glucagon


Credits to this creation: www.tcet.unt.edu
 
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